Discovery of Largest Protein in Algae Reveals New Strategies for Toxin Assembly

Researchers at UC San Diego's Scripps Institution of Oceanography have identified the largest protein ever discovered in biology, named PKZILLA-1.

Switching off inflammatory protein leads to longer, healthier lifespans in mice

Deactivating the inflammatory protein IL-11 significantly extends the lifespan and improves health in mice, showing promise for future applications in human aging and multimorbidity treatments.

Nemuri, a sleep-inducing gene links sleep and immune function in Drosophila

A sleep-inducing gene, nemuri, links sleep and immune function in Drosophila. Sleep inducing gene discovered also works as antimicrobial peptide.

The Inheritance You Did Not Ask For

The researcher provides evidence that paternal pathogenic infection has transgenerational impacts on offspring phenotypes. They discover that Toxoplasma gondii infection induces epigenetic changes, involving small RNAs, in mouse sperm, and demonstrate a mechanism involving these non-coding RNAs.

Antibodies as Potential Therapy for Obsessive Compulsive Disorder

Autoimmune-prone Annexin-A1 transgenic mice show high level of anxiety-like behavior and this was linked to high levels of an anxiogenic protein we christened Immno-moodulin. Antibodies against Immno-moodulin might be the future biologics for mental disorders.