Research Update

Stay informed with Research Updates as we bring you the latest breakthroughs and advancements in the field of biology. Our updates provide concise and accurate summaries of cutting-edge research, ensuring you stay current with the ever-evolving landscape of biological sciences. From innovative methodologies and emerging technologies to pivotal discoveries and their implications, Research Updates offers valuable insights for students, professionals, and enthusiasts alike. Keep pace with the rapid progress in biology and deepen your understanding of the natural world with our regularly updated content.

Research Update

Remdesivir for Potential Treatment of COVID-19: A Chemical View

Remdesivir (Gilead), an investigational broad-spectrum IV antiviral drug that is active against SARS-CoV-2 and other corona-viruses in vitro and in animal models.

Structures of coronavirus spike proteins complexed with the antibody.

Research Update

Molecular Mechanism for Antibody-Dependent Enhancement of Coronavirus Entry

Antibody-Dependent Enhancement occurs when antibodies facilitate viral entry into host cells and enhance viral infection. ADE is found to be associated with a variety of viruses, mostly with flaviviruses. Detailed molecular mechanism for Antibody-Dependent Enhancement of coronavirus entry is still unknown.

Research Update

Remdesivir and chloroquine effectively inhibit the novel coronavirus in vitro

These findings published in Nature reveal that remdesivir and chloroquine are highly effective in the control of 2019-nCoV infection in vitro.

Research Update

Researchers isolated gut bacteria that can prevent and cure rotavirus infection

The presence of specific microbiota, or microorganisms that live in the digestive tract, can prevent and cure rotavirus infection, which is the leading cause of severe, life-threatening diarrhea in children worldwide, according to a new study.

Research Update

Scientists found 5' NAD Cap in Human promotes RNA Decay

Mammalian cells contains NAD+-capped mRNAs and degraded by DXO family enzymes and scientists found that 5' end Nicotinamide Adenine Dinucleotide cap in human cells promotes RNA decay through DXO-Mediated deNADding.

Research Update

Poly(A) RNAs Decay Triggered by PNPT1 Released from Mitochondria in Apoptosis

Apoptosis studies has mostly focused on protein degradation by the caspases, MOMP and DNA fragmentation but little is known about the fate of RNA. Judy Lieberman discovered new mechanism of RNA decay.

Research Update

Antibodies as Potential Therapy for Obsessive Compulsive Disorder

Autoimmune-prone Annexin-A1 transgenic mice show high level of anxiety-like behavior and this was linked to high levels of an anxiogenic protein we christened Immno-moodulin. Antibodies against Immno-moodulin might be the future biologics for mental disorders.

Research Update

Repurposing of Potential Drugs - Potential Novel COVID-19 Medicine

Existing antivirals and knowledge gained from the SARS and MERS outbreaks gain traction as the fastest route to fight the current coronavirus epidemic.