Graduate Aptitude Test – Biotechnology (GAT-B) – Syllabus

The question paper for GAT-B will have two sections (Total 240 marks)

Section A (60 Marks)

Section A will have 60 compulsory multiple choice questions of the level of 10+2in the subjects: Physics, Chemistry, Mathematics and Biology. Each correct answer is of One (1) mark. There will be negative marking and for each wrong answer, Half (1/2 or 0.5) mark will be deducted.

Section B (180 Marks)

Section B will have multiple choice questions of Bachelor’s (Graduate) level requiring thinking and analysis. There will be questions from Basic Biology, Life Sciences, Biotechnology and allied areas as per syllabus given here. There will be 100 questions out of which candidates will have to attempt 60 questions.

  • Each correct answer is of Three (3) marks.
  • There will be negative marking and for each wrong answer, One (1) mark will be deducted.
  • Un-answered/un-attempted question will be given Zero (0) mark.

Syllabus for Section A

Syllabus for Section A is of 10+2 level in the subjects of

  • Physics
  • Chemistry
  • Mathematics
  • Biology

 

Recommendation: 10+2 level NCERT books for Physics, Chemistry, Mathematics and Biology will be helpful.

 

Syllabus for Section B

Syllabus for Section B is of Graduate level as described below:

Biochemistry

Biomolecules-structure and functions; Biological membranes, structure, action potential and transport processes; Enzymes- classification, kinetics and mechanism of action; Basic concepts and designs of metabolism (carbohydrates, lipids, amino acids and nucleic acids) photosynthesis, respiration and electron transport chain; Bioenergetics.

Microbiology

Viruses- structure and classification; Microbial classification and diversity (bacterial, algal and fungal); Methods in microbiology; Microbial growth and nutrition; Aerobic and anaerobic respiration; Nitrogen fixation; Microbial diseases and host-pathogeninteraction.

Cell Biology

Prokaryotic and eukaryotic cell structure; Cell cycle and cell growth control; Cell-Cell communication, Cell signaling and signal transduction.

Molecular Biology

Molecular structure of genes and chromosomes; Mutations and mutagenesis; Nucleic acid replication, transcription, translation and their regulatory mechanisms in prokaryotes and eukaryotes; Mendelian inheritance; Gene interaction; Complementation; Linkage, genetics (plasmids, transformation, transduction, conjugation); Horizontal gene transfer and Transposable elements; RNA interference; DNA damage and repair; Chromosomal variation; Molecular basis of genetic diseases.

Applied Biology

Principles of microscopy-light, electron, fluorescent and confocal; Centrifugation- high speed and ultra; Principles of spectroscopy-UV, visible, CD, IR, FTIR, Raman, MS, NMR; Principles of chromatography- ion exchange, gel filtration, hydrophobic interaction, affinity, GC, HPLC, FPLC; Electrophoresis; Microarray.